SFMR RESEARCH

 

 

Clinicians, radiologists, statisticians, pathologists, programmers, physicists, computer specialists, research associates and breast cancer advocates work together on the SFMR to investigate clinically relevant research questions of value to women about breast imaging and breast cancer.

 

 

 

 

Risk-Based Breast Cancer Screening in Community Settings

 

Funding Provided By: National Cancer Institute

 Co-Principal Investigator: Karla Kerlikowske, MD, Professor of Medicine and Epidemiology and Biostatistics, University of California, San Francisco

Co-investigators: John Shepherd, PhD, Elad Ziv, MD, Jeff Tice, MD and Steve Cummings, University of California, San Francisco

 

The overall goal of this project is to determine the optimal risk-based screening strategies for women at risk for breast cancer using the NCI-funded Breast Cancer Surveillance Consortium and to evaluate how breast cancer risk can be used to promote appropriate and efficient breast cancer screening and risk reduction practices. New risk models are being developed to better identify women at high and low risk of breast cancer.

 

 

Subregional Breast Density and Cancer Risk

 

Funding Provided By: National Cancer Institute

Principal Investigator: John Shepherd, PhD, Associate Professor of Radiology, University of California, San Francisco

Co-investigator: Karla Kerlikowske, MD, University of California, San Francisco

 

The overall goal of this project is to determine if focal areas of breast density in the breast are more strongly associated with breast cancer risk than the volume of breast density in the entire breast.

 

 

Automated Density Measures for Estimating Breast Cancer

 

Funding Provided By: National Cancer Institute

Co-Principal Investigator: Karla Kerlikowske, MD, Professor of Medicine and Epidemiology and Biostatistics, University of California, San Francisco

Co-investigator: John Shepherd, PhD, University of California, San Francisco

 


The major goal of this study is compare automated measures of volumetric breast density to determine the measure most strongly associated with breast cancer risk and the measure that most accurately assesses change in breast density with respect to hormone therapy.

 

Comparative Effectiveness of Surveillance Modalities in Breast Cancer Survivors

 

Funding Provided By: Patient-Centered Outcomes Research Institute

Principal Investigator: Karen Wernli, PhD, Group Health Cooperative of Puget Sound

Co-investigator: Karla Kerlikowske, MD, University of California, San Francisco

 

The major goal of this project is to determine optimal surveillance strategies using breast MRI or diagnostic mammography or both for women after a diagnosis with breast cancer.

 

 

Effectiveness of Pre-Operative MRI in Breast Cancer Surgery and Outcomes

 

Funding Provided By: National Cancer Institute

Principal Investigator: Tracy Onega, PhD, Geisel School of Medicine at Dartmouth

Co-investigator: Karla Kerlikowske, MD, University of California, San Francisco

 

 

The major goal of this project is to provide the first large-scale assessment of how preoperative breast MRI influences surgical treatment approaches among breast cancer patients, specifically, mastectomy vs. breast conserving treatment.

 

Breast Cancer Surveillance Consortium Data Resource

 

Funding Provided By: National Cancer Institute

 Co-Principal Investigator: Karla Kerlikowske, MD, Professor of Medicine and Epidemiology and Biostatistics, University of California, San Francisco

 Provide access to risk factor, breast imaging, cancer and vital status information to investigators proposing research questions for manuscripts and grants.